Hospital Universitario Nuestra Seora de Candelaria

Unidad de Investigacin
Publicaciones destacadas
  • Flores C, Ma SF, Pino-Yanes M, Wade MS, Perez-Mendez L, Kittles RA, Wang D, Papaiahgari S, Ford JG, Kumar R, Garcia JGN. (2011) African ancestry is associated with asthma risk in African Americans. PLoS ONE, in press.
  • Han YJ, Ma SF, Wade MS, Flores C, Garcia JGN. (2011) An intronic MYLK genetic variant associated with inflammatory lung diseases regulates promoter activity of the smooth muscle myosin light chain kinase. Journal of Molecular Medicine, in press. (http://www.ncbi.nlm.nih.gov/pubmed?term=22015949)
  • Pino-Yanes M, Sanchez-Machin I, Cumplido J, Figueroa J, Torres-Galvan MJ, Gonzalez R, Corrales A, Acosta Fernandez O, Garcia-Robaina JC, Carrillo T, Sanchez-Palacios A, Villar J, Hernandez M, Flores C. (2011) IRAK3 gene variants associate with asthma in a replication study in the Spanish population. Journal of Allergy and Clinical Immunology, in press. (http://www.ncbi.nlm.nih.gov/pubmed?term=22070913)
  • Pino-Yanes M, Ma SF, Sun X, Tejera P, Corrales A, Blanco J, Perez-Mendez L, Espinosa E, Muriel A, Blanch L, Garcia JGN, Villar J, Flores C. (2011) Interleukin-1 receptor-associated kinase 3 gene associates with susceptibility to acute lung injury. American Journal of Respiratory Cell and Molecular Biology 45: 740-745. (http://www.ncbi.nlm.nih.gov/pubmed?term=21297081)
  • Pino-Yanes M, Corrales A, Basaldua S, Hernandez A, Guerra L, Villar J, Flores C. (2011) North African influences and potential bias in case-control association studies in the Spanish population. PLoS ONE 6: e18389. (http://www.ncbi.nlm.nih.gov/pubmed?term=21479138)
  • Sun X, Ma SF, Wade MS, Flores C, Pino-Yanes M,  Moitra J, Ober C, Kittles R, Hussain A, Ford JG, Garcia JGN. (2010) Functional variants of sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility. Journal of Allergy and Clinical Immunology 126: 241-249. (http://www.ncbi.nlm.nih.gov/pubmed?term=20624651)
  • Pino-Yanes M, Corrales A, Casula M, Blanco J, Muriel A, Espinosa E, Garcia-Bello M, Torres A, Ferrer M, Zavala E, Villar J, Flores C. (2010) Common variants of TLR1 associate with organ dysfunction and sustained pro-inflammatory responses during sepsis. PLoS ONE 5: e13759. (http://www.ncbi.nlm.nih.gov/pubmed?term=21048935)
  • Flores C, Perez-Mendez L, Maca-Meyer N, Muriel A, Espinosa E, Blanco J, Sangüesa R, Muros M, Garcia JG, Villar J; for the GRECIA and Gen-SEP groups. (2009) A common haplotype of the LBP gene predisposes to severe sepsis. Critical Care Medicine 37: 2759-2766. (http://www.ncbi.nlm.nih.gov/pubmed?term=19707138)
  • Flores C, Ma SF, Maresso K, Ober C, Garcia JGN. (2007) A variant of the myosin light chain kinase gene (MYLK) is associated with severe asthma in African Americans. Genetic Epidemiology 31: 296-305. (http://www.ncbi.nlm.nih.gov/pubmed?term=17266121)
  • Flores C, Maca-Meyer N, Perez-Mendez L, Sangüesa R, Espinosa E, Blanco J, Villar J. (2006) A CXCL2 tandem repeat promoter polymorphism is associated with susceptibility to severe sepsis in the Spanish population. Genes and Immunity 7: 141-149. (http://www.ncbi.nlm.nih.gov/pubmed?term=16421598)